Germ Tube Induction Test Comparing Total of Six Liquid and Three Solid Media in Candida albicans

Invasive candidiasis (IC) has a high mortality rate of 70%, thus diagnosis should be established without delay. Given its fast result, serological test such as β-d-glucan (BDG) is one alternative modalities. However, it lacks specificity. Candida albicans germ tube antibody (CAGTA) an which sensitivity 76.2% and specificity 80.3%. Manufacturing CAGTA requires provision specific antigen. In this study, various culture media were tested to find the best for induction. This study was experimental in vitro study. The number length recorded two- three-hour incubation periods. A total six samples containing C. ATCC 90028, four wild type strains, krusei strain used. Nine induce formation: human sheep serum, fetal bovine mueller hinton agar broth, tryptic soy brain heart infusion broth. At both periods, medium with highest serum (p=0.001 p=0). longest found at two-hour period (p=0.005). Mueller broth (MHB) showed comparable results (p>0.05). Human superior inducer morphogenesis. use MHB recommended since fresh on regular basis impractical.